A variegated group of rheumatic disorders may occur in neonates. These disorders fall broadly into three groups: (i) transplacentally acquired immunological diseases such as neonatal lupus and neonatal antiphospholipid syndrome, (ii) genetic conditions such as the chronic infantile neurologic cutaneous and articular (CINCA) syndrome, and (iii) other miscellaneous disorders such as Kawasaki disease, Behçet’s disease and systemic JIA that may rarely present in neonatal period. Those fetuses and infants at greatest risk for transplacentally acquired disease due to the maternal rheumatic disease should be under close observation in order to anticipate perinatal problems and to take prompt preventive and therapeutic measures. Early recognition and referral to the pediatric rheumatologist is important for effective management of neonates and could help avoid the possible serious complications of these diseases. In addition, appropriate counseling of the parents and family of the affected neonate is necessary in transplacentally acquired and genetic diseases.

            Neonatal lupus and neonatal antiphospholipid syndrome are considered in vivo models of passively acquired autoimmune diseases, which result from the transplacental passage of specific maternal autoantibodies . There are many maternally derived autoantibodies which are capable of binding to fetal antigens, but only a few bring about neonatal illness. The most prominent fetal or neonatal effects are observed in transplacental passage of autoantibodies that have a causative role in the pathogenesis of autoimmune disease. Transport of maternal autoantibodies across the placenta is a selective process that begins at about 12 weeks of gestation and accelerates after 22 weeks of gestation. The bulk of transferred autoantibodies belong to the subclasses IgG₁/IgG₃, and the time course of clinical symptomatology often parallels the presumed half life of IgG immunoglobulins. Conversely, if autoantibodies are demonstrable in the neonate in the absence of clinical effects, they may only be an epiphenomenon of the maternal disease.

Neonatallupus erythematosus is an immune-mediated disease that rarely is associated with congenital heart block. Transient hepatitis, thrombocytopenia and anemia can also occur.

We describe a case of neonatal lupus erythematosus and review the clinical and laboratory manifestations of this rare disease. Its only clinical sign might be an annular facial rash. The rash is usually diagnostic, but can be confused with other annular lesions. Because of the possible serious complications of undiagnosed lupus, a thorough evaluation of both child and mother is required when this diagnosis is entertained.

            CINCA syndrome is a member of the rapidly expanding family of autoinflammatory disorders characterized by self-resolving attacks of fever accompanied by somewhat specific clinical features . These disorders have been extensively characterized recently, with a growing identification of genes involved in the pathogenesis.

This review focuses on recent advances relevant to primary-care physicians in the understanding of neonatal rheumatic diseases. The clinical features and possible pathogenic mechanisms of these diseases are described, with particular emphasis on their early clinical recognition. The literature search engines included PubMed, MEDLINE and Science Citation Index. The relevant articles were also identified by searching the references of available meta-analyses and review articles, and bibliography of pertinent references. 

NEONATAL LUPUS

Neonatal lupus erythematosus is an uncommon immune-mediated disease associated with the transplacental transfer of maternal immunoglobulin G autoantibodies. In 95% of cases the autoantibody is anti-Ro (SS-A), but it can be anti-La (SS-B) or anti-U₁RNP.Any of these autoantibodies can be found alone or in combination. There are even reports of histologically documented cases of neonatal lupus erythematosus where none of the above-listed antibodies were found. This finding suggests that some cases can be mediated by antibodies other than anti-Ro (SS-A), anti-La (SS-B) or anti-U₁RNP or perhaps by some factor or cofactor yet to be determined. In cases where only anti-U₁RNP antibodies are found, only cutaneous disease has been reported

A child will develop neonatal lupus erythematosus simply because its pregnant mother has anti-Ro (SS-A) antibodies. Neonatal lupus erythematosus occurs only in about 1% of these neonates. If a anti-Ro (SS-A)-positive mother has one child with neonatal lupus erythematosus, only 25% of subsequent children born to this mother will be so affected.These numbers are low, which is another reason to suspect a cofactor is involved in the pathogenesis of neonatal lupus erythematosus. Although congenital heart block can be found with this condition, it is rare. Its incidence ranges from 15% to 30% of affected infants.This form of congenital heart block is associated with high morbidity; 50% to 70% of patients require pacemakers. Transient forms of hepatitis, thrombocytopenia, and anemia can also occur.

Skin lesions and heart block are seen simultaneously in less than 10% of patients with neonatal lupus erythematosus.Cutaneous lesions consist of transient nonscarring erythematous annular plaques with a predilection for periorbital and photodistributed areas. Lesions generally appear within the first 2 months of life and resolve within 4 to 6 months when maternal antibodies disappear.Rarely, remnant telangiectasias can occur at previously affected sites.

A considerable proportion of mothers of affected infants are asymptomatic (40%). They might have Sjöogren’s syndrome, systemic lupus erythematosus, rheumatoid arthritis, overlap syndrome, or even leukocytoclastic vasculitis.Asymptomatic mothers do not invariably become ill, and if they do develop lupus erythematosus, it is not likely to be life threatening.Although neonatal lupus erythematosus has a very characteristic appearance, tinea faciei, a photodistributed drug eruption, urticaria, and annular erythemas are in the differential diagnosis. The diagnosis of neonatal lupus erythematosus is generally based on clinical findings when there are maternal and or neonatal autoantibodies. Determination of titers for antinuclear antibody, anti-Ro (SS-A), anti-La (SS-B) and anti-U₁RNP antibody is recommended for diagnosis. Liver function tests and a complete blood count should also be obtained. Skin biopsy is usually not required to establish the diagnosis. Histologic findings are similar to those of subacute cutaneous lupus erythematosus. All patients suspected of having neonatal lupus should have a thorough cardiac examination.

Management of the cutaneous lesions of neonatal lupus erythematosus requires sun avoidance, sunscreen, and low-potency topical corticosteroids to hasten resolution.

Neonatal lupus is a rare disease of the developing fetus and neonate acquired from the transplacental passage of specific maternal autoantibodies, in particular those directed against the extractable nuclear antigens Ro (also called SSA) and La (also called SSB) . Anti-Ro/La antibodies are present in a high percentage of patients with systemic lupus erythematosus (SLE) and Sjögren’s syndrome, but mothers with a known connective tissue disease and positive anti-Ro/La antibodies have only about 1-5% risk of delivering a child with neonatal lupus . On the other hand, neonatal lupus can be seen in the offspring of mothers who do not have any signs or symptoms of a connective tissue disorder, and the first demonstration of anti-Ro/La antibodies in these mothers occurs during the pregnancy or after delivery of an affected child.  

Clinical features

            The clinical features most clearly associated with neonatal lupus include cardiac disease, skin disease, hepatobiliary disease and cytopenia. The noncardiac manifestations of neonatal lupus are generally transient, resolving by 6 months of life coincident with the disappearance of maternal autoantibodies from the infant’s circulation. The most frequent lesion of cardiac neonatal lupus is complete (i.e., third degree) heart block, which is almost always permanent.

The classic presentation of neonatal lupus is one of a fetus or newborn discovered to have a slow heart rate due to congenital heart block in the absence of a structural heart disease. Many cases are discovered in utero, most commonly between 18 and 24 weeks of gestation. The identification of fetal bradycardia (i.e., heart rate less than 120 per minute) by either auscultation or routine obstetric ultrasound requires that the mother be referred for immediate fetal echocardiography to confirm the presence of heart block and to document the degree of the block. Autoimmune-associated congenital heart block can be first, second, or third degree, and may or may not be progressive after detection in utero or postnatally . Only second or third degree heart block is clinically manifested as bradycardia. It is estimated that up to one third of pregnancies complicated by fetal complete heart block result in intrauterine death, which is usually related to intractable heart failure and development of hydrops fetalis. Besides congenital heart block, other cardiac manifestations have been reported, such as myocarditis, dilated cardiomyopathy, sinus bradycardia, QT interval prolongation and, rarely, structural heart defects .

The skin rash of neonatal lupus characteristically appears a few days or weeks after birth, particularly after sun exposure. It consists of annular  or elliptical erythematosus plaques   most often located on the scalp, face and extremities. Skin lesions are transient, lasting weeks to months; these usually resolve without scarring. Hypopigmentation is frequent and may be a prominent feature. Rarely, remnant telangiectasias can occur at previously affected sites . The differential diagnosis of isolated cutaneous neonatal lupus includes tinea faciei, a photosensitive drug eruption, urticaria, seborrheic dermatitis and annular erythemas.

Hepatic dysfunction occurs in approximately 15% of cases with neonatal lupus and can present as severe liver failure in utero or after birth, transient cholestatic hepatitis and transient elevations of aminotransferases. Hepatobiliary disease may occur as the sole clinical manifestation, but is commonly associated with other manifestations of neonatal lupus .

Occasionally, newborns of mothers with anti-Ro/La antibodies may present with hematological manifestations including thrombocytopenia, anemia and neutropenia . There have also been several case reports of various neurological manifestations associated with neonatal lupus .

CUTANEUS NEONATAL LUPUS

Pathogenesis

            Presumably, the fetus develops normally until maternal IgG antibodies against the Ro and La proteins are actively transported across the placenta beginning at 12 weeks of gestation. Although the Ro and La proteins are normally intracellular and thus inaccessible to circulating antibodies, they are expressed on the developing fetal heart at different stages of gestation. It has been demonstrated that anti-Ro/La antibodies bind to fetal but not adult heart, and direct binding to fetal cardiac proteins may trigger an inflammatory response and cause tissue damage . Despite exposure to the identical circulating autoantibodies, the maternal heart is never affected.   

            The exact pathogenetic mechanism of non-cardiac manifestations is still unknown, but it has been hypothesized that the timing of transplacental passage of maternal autoantibodies coincides with the period of maximal vulnerability of selected fetal organs .

Finally, it should be emphasized that specific maternal autoantibodies are probably necessary, but are not sufficient, for development of neonatal lupus. Several concomitant maternal, fetal or environmental risk factors may contribute to the pathogenesis of this disease.

Management

            Prior to the development of fetal echocardiography, auscultatory evidence of regular bradycardia alerted the clinician to the congenital heart block, which could only be confirmed after birth. Fetal echocardiography is now used to establish the diagnosis of congenital heart block and it is recommended that the fetuses of all women with anti-Ro/La antibodies be evaluated by serial echocardiography. Echocardiograms are done weekly from 16 to 26 weeks and every other week until 32 weeks. A recent major advance in echocardiography was the development of a new non-invasive Doppler technique to measure the mechanical PR interval, which has made possible the in utero detection of first-degree heart block in the absence of an electrocardiogram. This technique allows earlier diagnosis and has paved the way for effective prenatal treatment in fetuses with incomplete heart block .

            The most common prenatal interventions attempted are systemic glucocorticosteroids and medications to treat heart failure. The rationale for treatment of identified heart block with glucocorticosteroids is to diminish the cardiac inflammatory injury and to lower the maternal autoimmune response. Dexamethasone, which is not metabolized by the placenta and is available to the fetus in an active form, is given at a dose of 4 mg/day. Fetal risks secondary to dexamethasone include oligohydramnios, intrauterine growth retardation and adrenal suppression. Sympathomimetics, diuretics and fetal pacing are reserved for those cases where the fetus is in a life-threatening situation with hydrops and deteriorating cardiac function .

Postnatal treatment of the symptomatic infant with complete heart block is based on pacemaker implantation, and supportive treatment for low output or congestive heart failure. 

Cutaneous manifestations of neonatal lupus generally do not require any treatment; however; topical application of a mild glucocorticosteroid cream may hasten the resolution of the lesions and be used for cosmetic reasons. All infants whose mothers have anti Ro/La antibodies should be protected from excessive exposure to the sun, which may induce or exacerbate skin lesions. In most cases, hepatobiliary and hematological manifestations are self-limited and the usual approach to management is reassurance to the parents and continued observation of the infant (including determination of titers for antinuclear antibodies and antibodies against extractable nuclear antigens, liver function tests, complete blood count and electrocardiogram) at least until transplacentally acquired autoantibodies become undetectable.           

Prognosis     

Nearly all children with complete heart block require implantation of a pacemaker at some point in their lives, frequently in the neonatal period . Despite early pacing, complete heart block carries high neonatal morbidity and high mortality during the first 12 months of life .

If a mother has already had one child with congenital heart block, there is approximately a 15 to 20% risk of having another child with the same problem, supporting close fetal echocardiographic monitoring and considering therapeutic interventions .

Apart from cardiac disease, children with neonatal lupus grow and develop normally. They have only a slightly higher risk for developing autoimmune disease later in life attributable to the genetic predisposition . Parents of these infants should be counseled that the risk of their offspring developing autoimmune diseases is similar to the risk in children of women with SLE or another connective tissue disease.  

NEONATAL ANTIPHOSPHOLIPID SYNDROME

            Neonatal antiphospholipid syndrome (APS) is a rare clinical entity characterized by neonatal thrombotic disease [3]. Autoantibodies that have been causally associated with neonatal APS include antiphospholipid antibodies (aPL), namely the β₂ glycoprotein I – dependent anticardiolipin antibodies and lupus anticoagulants. These autoantibodies have a well-recognized pathogenic role in thrombotic diathesis and have been associated with a number of obstetric complications such as recurrent pregnancy loss, pre-eclampsia, fetal growth retardation and pre-term delivery [26]. While women with aPL  show an unusually high incidence of pregnancy complications, the aPL-related thrombosis in their offspring seems to be exceedingly rare. The low frequency of neonatal thrombosis has been attributed to the lack of the most known “second hit” risk factors in infants (such as atherosclerosis, cigarette smoking, oral contraceptives etc.), and to a low transplacental passage of IgG2 subclass of aPL, which are responsible for most clinical pathogenicity .

            Neonatal thromboses associated with transplacentally acquired aPL were most commonly described in cerebral vessels and abdominal organs; however, vascular occlusion in APS may involve the arteries and veins at any level of the vascular tree and in all organ systems . Special concern is needed particularly when dealing with aPL-positive infants who are exposed to other acquired thrombotic risk factors (i.e., central vascular catheters, sepsis, prematurity, congenital heart disease), and possibly inherited prothrombotic disorders (i.e., deficiencies of antithrombin III, protein C, protein S, factor V Leiden mutation). There have also been scattered reports of thrombotic events in the fetuses of aPL-positive women, resulting from intra-uterine exposure to aPL .

            Both aPL and anti-Ro/La antibodies may be simultaneously present in a woman with connective tissue disease making the distinction between neonatal lupus and neonatal APS sometimes difficult . In fact, some of the hematological and neurological manifestations reported in neonatal lupus could be related to the presence of aPL . At the present time, however, the exact clinical criteria for these clinical entities are not available.     

CHRONIC INFANTILE NEUROLOGIC CUTANEOUS AND ARTICULAR (CINCA) SYNDROME     

CINCA syndrome is a rare congenital inflammatory disease characterized by a triad of cutaneous rash, chronic meningitis and arthropathy . The gene defective in CINCA syndrome (CIAS1 gene; so named for cold-induced autoinflammatory syndrome) was identified by positional cloning and encodes a 920-amino acid protein cryopyrin, which is involved in the regulation of apoptosis . The CIAS1 gene is also the site of mutations causing two other autoinflammatory disorders, Muckle-Wells syndrome and familial cold autoinflammatory syndrome . Several distinct mutations have been identified in CIAS1 gene, but there is no apparent clustering of mutations associated with particular illness. Because of clinical similarities between these syndromes and the same apparent genetic basis, it has been proposed that they represent a spectrum of disease, with familial cold autoinflammatory syndrome the mildest and CINCA syndrome the most severe. Mutations in CIAS1 gene were only identified in approximately half of the patients with CINCA syndrome, which raises the possibility of genetic heterogeneity . 

The most striking feature of CINCA syndrome is the onset in the neonatal period. Persistent and migratory urticarial rash is often present at birth or develops within the first weeks of life. It can be confused with a systemic JIA rash, but is more pronounced and present for the life of the patient [42]. The joint manifestations usually begin in the first year of life and most commonly involve knees, ankles, elbows, wrists, hands and feet. They could be limited to mild arthritis during flare-ups or present with severe deforming arthropathy with typical radiographic changes . Joint enlargement in CINCA syndrome is described as hard and bony with deformities from epiphyseal and growth cartilage overgrowth, rather than the soft tissue and synovial proliferation seen in JIA. The most distinctive changes occur in the metaphyses and epiphyses of the femur, radius and tibia, resulting in premature growth plate closure and shortened long bones. A premature patellar ossification is frequent with a subsequent overgrowth of the patella. Neurological impairment results from chronic meningeal inflammation and is characterized by symptoms indicating meningeal irritation (i.e., headaches, vomiting, seizures, spastic diplegia) and progressive cognitive impairment. Significant sensory abnormalities including ocular manifestations, perceptive deafness and hoarseness commonly occur in older patients. In the worst cases, eye involvement can lead to a progressive visual defect and sometimes to blindness [45]. Distinctive morphological features with frontal bossing, hypoplastic midface, shortening of distal limbs with clubbing of the fingers and growth retardation have been described.

Laboratory investigations reveal iron-resistant hypochromic anemia, leukocytosis with neutrophilia and eosinophilia, high platelet counts, elevated erythrocyte sedimentation rate and polyclonal hypergammaglobulinemia. There are usually no autoantibodies or antigen-specific T-cells.

The course is one of a chronic, persistent inflammatory disease with numerous flare-ups associating fever, hepatosplenomegaly and lymphadenopathy. Significant musculoskeletal functional disabilities occur in more than 50% of those affected, and severe failure to thrive and short stature are present in virtually all patients. Progressive neurological involvement with consequent developmental delay can occur with time. The mainstay of current therapy for CINCA syndrome consists of symptomatic relief with the use of nonsteroidal anti-inflammatory drugs and glucocorticosteroids. Patients may also benefit from physiotherapy, splinting and occupational therapy. No therapeutic approach has been effective in altering the course of the disease.

OTHER DISORDERS

Systemic juvenile idiopathic arthritis (JIA)

            Neonatal onset of systemic JIA (Still’s disease) is exceedingly rare, but needs to be considered in the differential diagnosis of a neonatal rash associated with systemic inflammatory signs . A neonate with evanescent rash that appeared on the second day of life in association with fever has been reported . Over the first weeks of life, the infant developed lymphadenopathy and hepatosplenomegaly. At 15 months he presented with arthritis of the right knee joint, confirming the diagnosis of systemic JIA.      ’

Behçet’s disease

A transient form of Behçet’s disease may develop in a neonate of a mother with this disease. In all reported neonatal cases, mothers had oral and genital ulceration during the pregnancy . The condition is thought to be transmitted by an immune mechanism similar to the mechanism of neonatal lupus; however, the causative autoantibodies for neonatal Behçet’s disease have not been identified. The most common features of neonatal Behçet’s disease include fever, orogenital ulcerations, pustulonecrotic skin lesions, bloody diarrhea, stridor and intrauterine growth retardation. A case of transient neonatal Behçet’s disease with life-threatening complications has also been reported. This baby developed pyrexia, blood-streaked diarrhea, vasculitic skin lesions and recurrent oral and pharyngeal ulcers, resulting in progressive inspiratory stridor and respiratory arrest . Clinical manifestations of neonatal Behçet’s disease usually develop within 1 week of birth and resolve by the age of 8 weeks, supporting the hypothesis that the disease is caused by the transplacental passage of maternal antibodies. Healing of the severe ulceration may result in extensive scarring and therapeutic intervention with glucocorticosteroids is recommended after diagnosis. Before applying this treatment, a disseminated infection (e.g. herpesvirus, Staphylococcus) must be excluded.     

Polyarteritis nodosa and other rare vasculitides

Vasculitis in a neonate born to a mother with vasculitis is a rare event and only few isolated cases have been described. At least three cases of neonatal vasculitis have been reported in infants born to mothers with cutaneous polyarteritis nodosa [54-56]. During the neonatal period these infants developed cutaneous vasculitis manifested by livedo reticularis, cutaneous nodules and acral necrosis. In all the cases, the vasculitis was confined to early infancy, suggesting that the disease was caused by a maternal factor that crossed the placenta.     

Kawasaki disease

Kawasaki disease is rarely encountered in the neonatal period. Of the 105,755 patients with Kawasaki disease included in the Japanese database over 25 years, only six were neonates . The rarity of disease in neonates has been explained by the protective effects of the transplacentally transferred maternal IgG immunoglobulins. Alternatively, the rare incidence rate at this age may be explained by infection theory, since neonates usually stay at home and seldom have chance to be exposed to the infectious agents. The reported neonatal cases had a rapid and severe course, and usually presented with atypical clinical features. In particular, they had a higher incidence of cardiac complications and usually did not fulfill the established diagnostic criteria of Kawasaki disease .

Other miscellaneous disorders

A number of other unrelated disorders may present in the neonatal period and should be considered in the differential diagnosis. They include hyper-IgD syndrome, acute febrile neutrophilic dermatosis (Sweet’s syndrome), histiocytosis, mastocytosis, neonatal infections, as well as selected metabolic diseases and primary immunodeficiencies in which autoimmune disorders may occur . 

REFERENCES

1. Buyon JP. Neonatal lupus. Curr Opin Rheumatol 1996;8:485-90.
2. Provost TT, Watson R, Simmons-O’Brien E. Significance of anti-Ro (SS-A) antibody in evaluation of patients with cutaneous manifestations of a connective tissue disease. J Am Acad Dermatol 1996;35(2 Pt 1):147-69.
3. Bunyon JP. Neonatal lupus: bedside to bench and back. Scand J Rheumatol 1996;25:271-6.
4. Neonatal lupus erythematosus. In: Hurwitz S. Clinical pediatric dermatology: a textbook of skin disorders of childhood and adolescence. 2nd ed. Philadelphia: W B Saunders, 1993:567-9.
5. Jaworsky C. Connective tissue diseases. In: Elder D, Elenitas R, Jaworsky C, Johnson B Jr, editors. Lever’s histopathology of the skin. 8th ed. Philadelphia: Lippincott-Raven; 1997:260.
6. Watson RM, Lane AT, Barnett NK, Bias WB, Arnett FC, Provost TT. Neonatal lupus erythematosus. A clinical, serological and immunogenetic study with review of the literature. Medicine 1984;63:362-78.
7. Chung ET, Buyon JP. Neonatal lupus syndromes. Rheum Dis Clin North Am 1997; 23: 31-53.
8. Brucato A, Cimaz R, Stramba-Badiale M. Neonatal lupus. Clin Rev Allergy Immunol 2002; 23: 279-99.
9. Crowley E, Frieden IJ. Neonatal lupus erythematosus: an unusual congenital presentation with cutaneous atrophy, erosions, alopecia, and pancytopenia. Pediatr Dermatol 1998;15:38-42.
10. Esterly NB. Neonatal lupus erythematosus. Pediatr Dermatol 1986;3:417-24.
11. Dickerson PA, Prendiville JS. Thrombocytopenia and hepatosplenomegaly in a newborn. Pediatr Dermatol 1989;6:346-8.
12. Watson R, Kang JE, May M, Hudak M, Kickler T, Provost TT. Thrombocytopenia in the neonatal lupus syndrome. Arch Dermatol 1988;124:560-3.
13. Wolach B, Choc L, Pomeranz A, Ben Ari Y, Douer D, Metzker A. Aplastic anemia in neonatal lupus. Am J Dis Child 1993;147:941-4.
14. Thorton CM, Eichenfeld LF, Shinall EA, et al. Cutaneous telangiectases in neonatal lupus erythematosus. J Am Acad Dermatol 1995;33:19-25.
15. Avcin T, Cimaz R, Meroni PL. Recent advances in antiphospholipid antibodies and antiphospholipid syndromes in pediatric populations. Lupus 2002; 11: 4-10.
16. Drenth JP, van der Meer JW. Hereditary periodic fever. N Engl J Med 2001; 345: 1748-57.
17. Brucato A, Doria A, Frassi M, et al. Pregnancy outcome in 100 women with autoimmune diseases and anti-Ro/SSA antibodies: a prospective controlled study. Lupus 2002; 11: 716-21.
18. Gladman G, Silverman ED, Yuk-Law, et al. Fetal echocardiographic screening of pregnancies of mothers with anti-Ro and/or anti-La antibodies. Am J Perinatol 2002; 19: 73-9.
19. Buyon JP, Hiebert R, Copel J, et al. Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry. J Am Coll Cardiol 1998; 31: 1658-66.
20. Askanase AD, Friedman DM, Copel J, et al. Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA/Ro-SSB/La antibodies. Lupus 2002; 11: 145-51.
21. Cimaz R, Stramba-Badiale M, Brucato A, Catelli L, Panzeri P, Meroni PL. QT interval prolongation in asymptomatic anti-SSA/Ro-positive infants without congenital heart block. Arthritis Rheum 2000; 43: 1049-53.
22. Brucato A, Cimaz R, Catelli L, Meroni P. Anti-Ro-associated sinus bradycardia in newborns. Circulation 2000; 102: E88-9.
23. Neiman AR, Lee LA, Weston WL, Buyon JP. Cutaneous manifestations of neonatal lupus without heart block: characteristics of mothers and children enrolled in a national registry. J Pediatr 2000; 137: 674-80.
24. Laxer RM, Roberts EA, Gross KR, Britton JR, Cutz E, Dimmick J, Petty RE, Silverman ED. Liver disease in neonatal lupus erythematosus. J Pediatr 1990; 116: 238-42.
25. Lee LA, Sokol RJ, Buyon JP. Hepatobiliary disease in neonatal lupus: prevalence and clinical characteristics in cases enrolled in a national registry. Pediatrics 2002; 109: e11.
26. Kanagasegar S, Cimaz R, Kurien BT, Brucato A, Scofield RH. Neonatal lupus manifests as isolated neutropenia and mildly abnormal liver functions. J Rheumatol 2002; 29: 187-91.
27. Besson-Leaud L, Fontan D, Billeaud C, Sandler B. Neonatal lupus erythematosus and neurological involvement: an incidental association? Arch Pediatr 2002; 9: 503-5.
28. Prendiville JS, Cabral DA, Poskitt KJ, Au S, Sargent MA. Central nervous system involvement in neonatal lupus erythematosus. Pediatr Dermatol 2003; 20: 60-7.
29. Miranda ME, Tseng CE, Rashbaum W, et al. Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes. J Immunol 1998; 161: 5061-9.
30. Tran HB, Macardle PJ, Hiscock J, et al. Anti-La/SSB antibodies transported across the placenta bind apoptotic cells in fetal organs targeted in neonatal lupus. Arthritis Rheum 2002; 46: 1572-9.
31. Saleeb S, Copel J, Friedman D, Buyon JP. Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody-associated congenital heart block: retrospective review of the research registry for neonatal lupus. Arthritis Rheum 1999; 42: 2335-45.
32. Glickstein JS, Buyon JP, Friedman D. Pulsed Doppler echocardiographic assessment of the fetal PR interval. Am J Cardiology 2000; 86: 236-9.
33. Shinohara K, Miyagawa S, Fujita T, Aono T, Kidoguchi K. Neonatal lupus erythematosus: results of maternal corticosteroid therapy. Obstet Gynecol 1999; 93: 952-7.
34. Friedman DM, Rupel A, Glickstein J, Buyon JP. Congenital heart block in neonatal lupus: the pediatric cardiologist’s perspective. Indian J Pediatr 2002; 69: 517-22.
35. Eronen M, Sirèn MK, Ekblad H, Tikanoja T, Julkunen H, Paavilainen T. Short- and long-term outcome of children with congenital complete heart block diagnosed in utero or as a newborn. Pediatrics 2000; 106: 86-91.
36. Brucato A, Gasparini M, Vignati G, et al. Isolated congenital complete heart block. Longterm outcome of children and immunogenetic study. J Rheumatol 1995; 22: 541-3.
37. Martin V, Lee LA, Askanase AD, Katholi M, Buyon JP. Long-term followup of children with neonatal lupus and their unaffected siblings. Arthritis Rheum 2002; 46: 2377-83.
38. Geis W, Branch DW. Obstetric implications of antiphospholipid antibodies: pregnancy loss and other complications. Clin Obstet Gynecol 2001; 44: 2-10.
39. Navarro F, Doña-Naranjo MA, Villanueva I. Neonatal antiphospholipid syndrome. J Rheumatol 1997; 24: 1240-1. 
40. Sammaritano LR, Ng S, Sobel R, et al. Anticardiolipin IgG subclasses: association of IgG2 with arterial and/or venous thrombosis. Arthritis Rheum 1997; 40: 1998-2006.
41. Avcin T, Ambrozic A, Kuhar M, Rozman B. Thrombosis in children. Thromb Haemost 2003; 89: 1107.
42. Hage ML, Liu R, Marcheschi DG, Bowie JD, Allen NB, Macik BG. Fetal renal vein thrombosis, hydrops fetalis, and maternal lupus anticoagulant. A case report. Prenat Diagn 1994; 14: 873-7.
43. Brewster JA, Quenby SM, Alfirevic Z. Intra-uterine death due to umbilical cord thrombosis secondary to antiphospholipid syndrome. Lupus 1999; 8: 558-9.
44. Katayama I, Kondo S, Kawana S, Nishioka K, Nishiyama S. Neonatal lupus erythematosus with a high anticardiolipin antibody titer. Unusual variant of neonatal lupus erythematosus or early-onset systemic lupus erythematosus? J Am Acad Dermatol 1989; 21: 490-2.
45. Torbiak RP, Dent PB, Cockshott WP. NOMID – a neonatal syndrome of multisystem inflammation. Skeletal Radiol 1989; 18: 359-64.
46. Dollfus H, Hafner R, Hofmann HM, et al. Chronic infantile neurological cutaneous and articular/neonatal onset multisystem inflammatory disease syndrome: ocular manifestations in a recently recognized chronic inflammatory disease of childhood. Arch Ophthalmol 2000; 118: 1386-92.
47. Tsuchida S, Yamanaka T, Tsuchida R, Nakamura Y, Yashiro M, Yanagawa H. Epidemiology of infant Kawasaki disease with a report of the youngest neonatal case ever reported in Japan. Acta Paediatr 1996; 85: 995-7.
48. Bolz D, Arbenz U, Fanconi S, et al. Myocarditis and coronary dilatation in the 1st week of life: neonatal incomplete Kawasaki disease? Eur J Pediatr 1998; 157: 589-91.    
49. Stanley TV, Grimwood K. Classical Kawasaki disease in a neonate. Arch Dis Child Fetal Neonatal Ed 2002; 86: F135-6.
50. Fam AG, Siminovitch KA, Carette S, From L. Neonatal Behçet’s syndrome in an infant of a mother with the disease. Ann Rheum Dis 1981; 40: 509-12.
51. Lewis MA, Priestley BL. Transient neonatal Behçet’s disease. Arch Dis Child 1986; 61: 805-6.
52. Fain O, Mathieu E, Lachassinne E, et al. Neonatal Behçet’s disease. Am J Med 1995; 98: 310-1.
53. Guzelin G, Norton ME. Behçet syndrome associated with intrauterine growth restriction: a case report and review of the literature. J Perinatol 1997; 17: 318-20.
54. Stark AC, Bhakta B, Chamberlain MA, Dear P, Taylor PV. Life-threatening transient neonatal Behçet’s disease. Br J Rheumatol 1997; 36: 700-2.
55. Boren RJ, Everett MA. Cutaneous vasculitis in mother and infant. Arch Dermatol 1965; 92: 568-70.
56. Miller JJ, Fries JF. Simultaneous vasculitis in a mother and newborn infant. J Pediatr 1975; 87: 443-5.
57. Stone MS, Olson RR, Weismann DN, Giller RH, Goeken JA. Cutaneous vasculitis in the newborn of a mother with cutaneous polyarteritis nodosa. J Am Acad Dermatol 1993; 28: 101-5.
58. Gadoth N, Hershkovitch Y. Rheumatoid arthritis during the first year of life. Eur J Pediatr 1979; 132: 115-8.
59. Hoeger PH, Veelken N, Foeldvari I, Kurtze M, Foss HD. Neonatal onset of rash in Still’s disease. J Pediatr 2000; 137: 128-31.
60. Quartier P, Prieur AM. Immunodeficiency and genetic conditions that cause arthritis in childhood. Curr Rheumatol Rep 2002; 4: 483-93.
61. Abu-Ras R, Felser K, Rottem M. Maternal antiphospholipid syndrome presenting as neonatal lupus with congenital complete heart block in the fetus. IMAJ 2001; 3: 966-8.
62. Hariharan D, Manno CS, Seri I. Neonatal lupus erythematosus with microvascular hemolysis. J Pediatr Hematol Oncol 2000; 22: 351-4.
63. Besson-Leaud L, Fontan D, Billeaud C, Sandler B. Neonatal lupus erythematosus and neurologic involvement: an incidental association? Arch Pediatr 2002; 9: 503-5.
64. Prieur AM, Griscelli C. Arthropathy with rash, chronic meningitis, eye lesions, and mental retardation. J Pediatr 1981; 99: 79-83.
65. Hassink SG, Goldsmith DP. Neonatal onset multisystem inflammatory disease. Arthritis Rheum 1983; 26: 668-73.
66. Prieur AM. A recently recognized chronic inflammatory disease of early onset characterized by the triad of rash, central nervous system involvement and arthropathy. Clin Exp Rheumatol 2001; 19: 103-6.
67. Feldmann J, Prieur AM, Quartier P, et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am J Hum Genet 2002; 71: 198-203.
68. Aksentijevich I, Nowak M, Mallah M, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum 2002; 46: 3340-8.
69. Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001; 29: 301-5.
70. Hashkes PJ, Lovell DJ. Recognition of infantile-onset multisystem inflammatory disease as a unique entity. J Pediatr 1997; 130: 513-5.
71. Kaufman RA, Lovell DJ. Infantile-onset multisystem inflammatory disease: radiologic findings. Radiology 1986; 160: 741-6.

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Original Articles

Cow’s milk allergy related pediatric constipation: Appropriate time of milk tolerance (p ???-???)
M. A. El-Hodhod, N. T. Younis, Y. A. Zaitoun, S. D. Daoud
Published Online: Jun 25 2009 11:18AM
DOI: 10.1111/j.1399-3038.2009.00898.x
 

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Identification of the etiologies of chronic urticaria in children: A prospective study of 94 patients (p ???-???)
Orathai Jirapongsananuruk, Sureerat Pongpreuksa, Preeda Sangacharoenkit, Nualanong Visitsunthorn, Pakit Vichyanond
Published Online: Jun 25 2009 11:18AM
DOI: 10.1111/j.1399-3038.2009.00912.x
 

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Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children (p )
Mette Sørensen, Leila Allermann, Ulla Vogel, Paal Skytt Andersen, Cathrine Jespersgaard, Steffen Loft, Ole Raaschou-Nielsen
Published Online: Aug 6 2009 5:26AM
DOI: 10.1111/j.1399-3038.2009.00855.x
 

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Educational Clinical Case Series

Allergic rhinitis in the child and associated comorbidities (p )
Tania Sih, Olavo Mion
Published Online: Aug 2 2009 11:21PM
DOI: 10.1111/j.1399-3038.2009.00933.x
 

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Original Articles

The impact of ambient NO on online measurements of exhaled and nasal NO: The PIAMA study (p )
Ulrike Gehring, Marieke Oldenwening, Bert Brunekreef, Marjan H. Wieringa, Marjan Kerkhof, Henriette A. Smit, Cornelis K. van der Ent, Johan C. De Jongste
Published Online: Jul 17 2009 3:10AM
DOI: 10.1111/j.1399-3038.2009.00854.x
 

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Short Communications

Oral desensitization to milk: how to choose the starting dose! (p )
Francesca Mori, Neri Pucci, Maria Elisabetta Rossi, Maurizio de Martino, Chiara Azzari, Elio Novembre
Published Online: Jul 13 2009 9:51PM
DOI: 10.1111/j.1399-3038.2009.00917.x
 

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Original Articles

A systematic review of the importance of milk TGF- on immunological outcomes in the infant and young child (p )
Wendy H. Oddy, Francisco Rosales
Published Online: Jul 9 2009 5:26AM
DOI: 10.1111/j.1399-3038.2009.00913.x
 

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Contact to cat or dog, allergies and parental education (p )
Christian Joachim Apfelbacher, Markus Ollert, Johannes Ring, Heidrun Behrendt, Ursula Krämer
Published Online: Jul 8 2009 5:03AM
DOI: 10.1111/j.1399-3038.2009.00893.x
 

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A probiotic dairy product containing L. gasseri CECT5714 and L. coryniformis CECT5711 induces immunological changes in children suffering from allergy (p )
Ana Martínez-Cañavate, Saleta Sierra, Federico Lara-Villoslada, Julio Romero, José Maldonado, Julio Boza, Jordi Xaus, Mónica Olivares
Published Online: Jul 8 2009 5:03AM
DOI: 10.1111/j.1399-3038.2008.00833.x
 

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The Prevalence of food hypersensitivity in young adults (p )
M. Osterballe, C. G. Mortz, T. K. Hansen, K. E. Andersen, C. Bindslev-Jensen
Published Online: Jul 7 2009 1:29AM
DOI: 10.1111/j.1399-3038.2008.00842.x
 

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Allergic rhinitis in school-aged children with asthma – still under-diagnosed and under-treated? A retrospective study in a children’s hospital (p )
M. Ruokonen, M. Kaila, R. Haataja, M. Korppi, M. Paassilta
Published Online: Jul 5 2009 10:00PM
DOI: 10.1111/j.1399-3038.2009.00891.x
 

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Effects of pet exposure in the first year of life on respiratory and allergic symptoms in 7-yr-old children. The SIDRIA-2 study (p )
Enrico Lombardi, Marzia Simoni, Stefania La Grutta, Giovanni Viegi, Luigi Bisanti, Elisabetta Chellini, Valerio Dell’Orco, Enrica Migliore, Maria Grazia Petronio, Riccardo Pistelli, Franca Rusconi, Piersante Sestini, Francesco Forastiere, Claudia Galassi
Published Online: Jul 2 2009 9:54PM
DOI: 10.1111/j.1399-3038.2009.00910.x
 

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Review Articles

Specific oral tolerance induction (SOTI) in pediatric age: Clinical research or just routine practice? (p )
Stefano Miceli Sopo, Roberta Onesimo, Valentina Giorgio, Carlo Fundarò
Published Online: Jul 2 2009 4:23AM
DOI: 10.1111/j.1399-3038.2009.00922.x
 

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Probiotics and prebiotics in atopic dermatitis: review of the theoretical background and clinical evidence (p )
Leontien B. van der Aa, Hugo S.A. Heymans, Wim M.C. van Aalderen, Aline B. Sprikkelman
Published Online: Jul 2 2009 4:22AM
DOI: 10.1111/j.1399-3038.2009.00915.x
 

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Original Articles

Antigenic proteins of Lactobacillus acidophilus that are recognised by serum IgG antibodies in children with type 1 diabetes and coeliac disease (p )
Anna-Liisa Prangli, Meeme Utt, Ija Talja, Epp Sepp, Marika Mikelsaar, Tarvo Rajasalu, Oivi Uibo, Vallo Tillmann, Raivo Uibo
Published Online: Jul 2 2009 4:22AM
DOI: 10.1111/j.1399-3038.2009.00904.x
 

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Early exposure to solid foods and the development of eczema in children up to 4 years of age (p )
Manana Sariachvili, Jos Droste, Sandra Dom, Marjan Wieringa, Margo Hagendorens, Wim Stevens, Marc van Sprundel, Kristien Desager, Joost Weyler
Published Online: Jul 1 2009 11:06PM
DOI: 10.1111/j.1399-3038.2009.00899.x
 

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Clinical outcome and IL-17, IL-23, IL-27 and FOXP3 expression in peripheral blood mononuclear cells of pollen-allergic children during sublingual immunotherapy (p )
Kaisa Nieminen, Erkka Valovirta, Johannes Savolainen
Published Online: Jun 29 2009 9:42PM
DOI: 10.1111/j.1399-3038.2009.00920.x
 

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High intestinal IgA associates with reduced risk of IgE-associated allergic diseases (p )
Kaarina Kukkonen, Mikael Kuitunen, Tari Haahtela, Riitta Korpela, Tuija Poussa, Erkki Savilahti
Published Online: Jun 29 2009 9:40PM
DOI: 10.1111/j.1399-3038.2009.00907.x
 

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Acute allergic skin response as a new tool to evaluate the allergenicity of whey hydrolysates in a mouse model of orally induced cow’s milk allergy (p )
Betty C. A. M. van Esch, Bastiaan Schouten, Gerard A. Hofman, Ton van Baalen, Frans P. Nijkamp, Léon M. J. Knippels, Linette E. M. Willemsen, Johan Garssen
Published Online: Jun 26 2009 4:39AM
DOI: 10.1111/j.1399-3038.2009.00924.x
 

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Feasibility of a new method to collect exhaled breath condensate in pre-school children (p )
Philippe P. R. Rosias, Charlotte M. Robroeks, Kim D. van de Kant, Ger T. Rijkers, Luc J. Zimmermann, Constant P. van Schayck, Jan W. Heynens, Quirijn Jöbsis, Edward Dompeling
Published Online: Jun 26 2009 4:39AM
DOI: 10.1111/j.1399-3038.2009.00909.x
 

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Efficacy of tacrolimus 0.03% ointment as second-line treatment for children with moderate-to-severe atopic dermatitis: evidence from a randomized, double-blind non-inferiority trial vs. fluticasone 0.005% ointment (p )
N. Doss, M.-R. Kamoun, L. Dubertret, F. Cambazard, A. Remitz, M. Lahfa, Y. de Prost
Published Online: Jun 26 2009 4:38AM
DOI: 10.1111/j.1399-3038.2009.00895.x
 

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Maternal meat and fat consumption during pregnancy and suspected atopic eczema in Japanese infants aged 3–4 months: The Osaka Maternal and Child Health Study (p )
Kyoko Saito, Tetsuji Yokoyama, Yoshihiro Miyake, Satoshi Sasaki, Keiko Tanaka, Yukihiro Ohya, Yoshio Hirota
Published Online: Jun 23 2009 4:05AM
DOI: 10.1111/j.1399-3038.2009.00897.x
 

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Reduced IFN-- and enhanced IL-4-producing CD4⁺ cord blood T cells are associated with a higher risk for atopic dermatitis during the first 2 yr of life (p )
Gunda Herberth, Joachim Heinrich, Stefan Röder, Adina Figl, Michael Weiss, Ulrike Diez, Michael Borte, Olf Herbarth, Irina Lehmann
Published Online: Jun 23 2009 4:04AM
DOI: 10.1111/j.1399-3038.2009.00890.x
 

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Body mass index and acute asthma severity among children presenting to the emergency department (p )
Adit A. Ginde, Alfredo A. Santillan, Sunday Clark, Carlos A. Camargo Jr
Published Online: Jun 22 2009 2:32PM
DOI: 10.1111/j.1399-3038.2009.00911.x
 

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Early wheezing phenotypes and cognitive development of 3-yr-olds. Community-recruited birth cohort study (p )
Wieslaw Jedrychowski, Frederica P. Perera, Jeffery Jankowski, Umberto Maugeri, Dorota Mrozek-Budzyn, Elzbieta Mroz, Elzbieta Flak, Anita Skarupa, Susan Edwards, Ilona Lisowska-Miszczyk
Published Online: Jun 22 2009 2:32PM
DOI: 10.1111/j.1399-3038.2009.00905.x
 

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The ImmunoCAP^® rapid wheeze/rhinitis child test is useful in the initial allergy diagnosis of children with respiratory symptoms (p )
Philippe A. Eigenmann, Markus Kuenzli, Vincenzo D’Apuzzo, Rainer Kehrt, Walter Joerg, Michael Reinhardt, Magnus Rudengren, Magnus P. Borres, Roger P. Lauener
Published Online: Jun 22 2009 12:25PM
DOI: 10.1111/j.1399-3038.2009.00866.x
 

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IL13 variants are associated with total serum IgE and early sensitization to food allergens in children with atopic dermatitis (p )
Simona Eva Zitnik, Franz Rüschendorf, Sebastian Müller, Claudia Sengler, Young-Ae Lee, Rupino W. Griffioen, Paolo Meglio, Ulrich Wahn, Heiko Witt, Renate Nickel
Published Online: Feb 10 2009 8:26PM
DOI: 10.1111/j.1399-3038.2008.00815.x
 

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Clinical effects of a Long-term Educational Program for Children with Asthma – Aironet^®. A 1-yr randomized controlled trial (p )
Luciana Indinnimeo, Enea Bonci, Lucetta Capra, Stefania La Grutta, Francesca Monaco, Francesco Paravati, Giovanni Passalacqua, Gaetano Silvestre, Marzia Duse
Published Online: Jun 12 2009 5:47AM
DOI: 10.1111/j.1399-3038.2009.00857.x
 

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Exhaled nitric oxide and exercise-induced bronchoconstriction in young wheezy children – interactions with atopy (p )
L. Pekka Malmberg, Anna S. Pelkonen, Petri S. Mattila, Sari Hammarén-Malmi, Mika J. Mäkelä
Published Online: Jun 2 2009 9:56PM
DOI: 10.1111/j.1399-3038.2009.00858.x
 

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Increase of inflammatory markers after indoor renovation activities: The LISA birth cohort study (p )
Gunda Herberth, Reinhild Gubelt, Stefan Röder, Ursula Krämer, Roel P. F. Schins, Ulrike Diez, Michael Borte, Joachim Heinrich, H.-Erich Wichmann, Olf Herbarth, Irina Lehmann
Published Online: May 31 2009 10:01PM
DOI: 10.1111/j.1399-3038.2008.00819.x
 

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Lower-leg growth rates in children with asthma during treatment with ciclesonide and fluticasone propionate (p )
Lone Agertoft, Søren Pedersen
Published Online: Mar 23 2009 5:06AM
DOI: 10.1111/j.1399-3038.2009.00879.x
 

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Review Articles

Methodology and implications of knemometry in growth assessment of inhaled glucocorticoids (p )
O. D. Wolthers
Published Online: May 4 2009 3:33AM
DOI: 10.1111/j.1399-3038.2009.00882.x
 

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Original Articles

Cow’s milk allergy is associated with changes in urinary organic acid concentrations (p )
Heli Salmi, Mikael Kuitunen, Mirva Viljanen, Risto Lapatto
Published Online: Apr 22 2009 11:11PM
DOI: 10.1111/j.1399-3038.2009.00881.x
 

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Increased rate and greater severity of allergic reactions to insect sting among schoolchildren with atopic diseases (p )
Yael Graif, Orly Romano-Zelekha, Irit Livne, Manfred S. Green, Tamy Shohat
Published Online: Apr 21 2009 10:42PM
DOI: 10.1111/j.1399-3038.2009.00863.x
 

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Time trends of co-existing atopic conditions in Singapore school children: prevalence and related factors (p )
Xiao Shan Wang, Lynette P. Shek, Stefan Ma, Shu E Soh, Bee Wah Lee, Daniel Y. T. Goh
Published Online: Apr 21 2009 10:43PM
DOI: 10.1111/j.1399-3038.2009.00877.x
 

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Maturation of cytokine-producing capacity from birth to 1 yr of age (p )
Mikko Lappalainen, Marjut Roponen, Juha Pekkanen, Kati Huttunen, Maija-Riitta Hirvonen
Published Online: Apr 21 2009 10:43PM
DOI: 10.1111/j.1399-3038.2009.00865.x
 

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Asthma and rhinoconjunctivitis comorbidity: United airway disease or inherited target organs? (p )
Luis Garcia-Marcos, Teresa Rubi Ruiz, Gloria Garcia-Hernandez, Maria Morales Suarez-Varela, Jose Valverde-Molina, Manuel Sanchez-Solis
Published Online: Apr 7 2009 11:25PM
DOI: 10.1111/j.1399-3038.2009.00886.x
 

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Letters to the Editor

Intravenous immunoglobulin-induced neutropenia (p )
S. Khan, P. C. Doré, W. A. C. Sewell
Published Online: Apr 7 2009 11:24PM
DOI: 10.1111/j.1399-3038.2009.00885.x
 

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Original Articles

Modulation of in vivo and in vitro cytokine production over the course of pregnancy in allergic and non-allergic mothers (p )
Liza Anne Breckler, Jasmine Hale, Wiebke Jung, Lauren Westcott, Janet A. Dunstan, Catherine A. Thornton, Susan L. Prescott
Published Online: Mar 27 2009 4:05AM
DOI: 10.1111/j.1399-3038.2009.00880.x
 

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Efficacy of sublingual specific immunotherapy in intermittent and persistent allergic rhinitis in children: an observational case–control study on 171 patients. The EFESO-children Multicenter Trial (p )
Franca Acquistapace, Fabio Agostinis, Vincenzo Castella, Ahmad Kantar, Elio Novembre, Maria Rosaria Perrone, Michele Pietrasanta, Renato Sambugaro, Massimo Milani
Published Online: Mar 23 2009 5:06AM
DOI: 10.1111/j.1399-3038.2009.00860.x
 

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A randomized trial of lower leg and height growth in children with asthma treated with inhaled budesonide from a new dry powder inhaler (p )
Josefine Gradman, Ole D. Wolthers
Published Online: Mar 3 2009 9:03PM
DOI: 10.1111/j.1399-3038.2009.00875.x
 

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Short Communications

Nasopharyngeal aspirate cytokine levels 1 yr after severe respiratory syncytial virus infection (p )
Maria Pino, David J. Kelvin, Jesus F. Bermejo-Martin, Ana Alonso, Vanesa Matías, Alberto Tenorio, Lucia Rico, Jose M. Eiros, J. Castrodeza, Alfredo Blanco-Quiros, Julio Ardura, Raul Ortiz de Lejarazu
Published Online: Mar 2 2009 10:32PM
DOI: 10.1111/j.1399-3038.2009.00868.x
 

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Original Articles

The regulatory function of umbilical cord blood CD4⁺ CD25⁺ T cells stimulated with anti-CD3/anti-CD28 and exogenous interleukin (IL)-2 or IL-15 (p )
Chen-Cheng Lee, Syh-Jae Lin, Po-Jen Cheng, Ming-Ling Kuo
Published Online: Mar 2 2009 10:32PM
DOI: 10.1111/j.1399-3038.2008.00843.x
 

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Salmeterol/fluticasone propionate vs. double dose fluticasone propionate on lung function and asthma control in children (p )
Jacques de Blic, Ludmila Ogorodova, Rabih Klink, Irina Sidorenko, Arunas Valiulis, Jerzy Hofman, Olav Bennedbaek, Sally Anderton, Valerie Attali, Jean-Luc Desfougeres, Marc Poterre
Published Online: Feb 22 2009 10:47PM
DOI: 10.1111/j.1399-3038.2009.00861.x
 

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Food allergy after liver transplantation in children: a prospective study (p )
Ozlem Yilmaz Ozbek, Figen Ozcay, Zekai Avci, Aysegul Haberal, Mehmet Haberal
Published Online: Feb 22 2009 10:47PM
DOI: 10.1111/j.1399-3038.2009.00867.x
 

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Elevated cord blood IgE is associated with recurrent wheeze and atopy at 7 yrs in a high risk cohort (p )
Alexander Ferguson, Helen Dimich-Ward, Allan Becker, Wade Watson, Anne DyBuncio, Chris Carlsten, Moira Chan-Yeung
Published Online: Feb 19 2009 5:37AM
DOI: 10.1111/j.1399-3038.2009.00869.x
 

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Indoor environmental risk factors and seasonal variation of childhood asthma (p )
Yueh-Ying Han, Yung-Ling Lee, Yueliang Leon Guo
Published Online: Feb 19 2009 5:37AM
DOI: 10.1111/j.1399-3038.2009.00871.x
 

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High prevalence of sensitization to aeroallergens in children 4 yrs of age or younger with symptoms of allergic disease (p )
Adriana Baatenburg de Jong, Lambert D. Dikkeschei, Paul L. P. Brand
Published Online: Feb 19 2009 5:37AM
DOI: 10.1111/j.1399-3038.2009.00864.x
 

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Parental perceptions in egg allergy: Does egg challenge make a difference? (p )
Andrew Stewart Kemp, Clare Wendy Allen, Dianne Elisabeth Campbell
Published Online: Feb 19 2009 5:36AM
DOI: 10.1111/j.1399-3038.2009.00859.x
 

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Serum measurement of thymus and activation-regulated chemokine/CCL17 in children with atopic dermatitis: elevated normal levels in infancy and age-specific analysis in atopic dermatitis (p )
Takao Fujisawa, Mizuho Nagao, Yukiko Hiraguchi, Hajime Katsumata, Hisashi Nishimori, Kosei Iguchi, Yoshiko Kato, Masahito Higashiura, Izumi Ogawauchi, Kunihiko Tamaki
Published Online: Feb 19 2009 5:36AM
DOI: 10.1111/j.1399-3038.2009.00851.x
 

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Accuracy of ImmunoCAP^® Rapid in the diagnosis of allergic sensitization in children between 1 and 14 years with recurrent wheezing: The IReNE study (p )
Carlos Diaz-Vazquez, María José Torregrosa-Bertet, Ignacio Carvajal-Urueña, Alfredo Cano-Garcinuño, Emili Fos-Escrivà, Amparo García-Gallego, Ferrán López-Cacho, Mª Carmen Monzón-Fueyo, Xavier M. Pérez-Porcuna, Mª Luisa Ridao-Redondo
Published Online: Feb 10 2009 7:55PM
DOI: 10.1111/j.1399-3038.2008.00827.x
 

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Transfer of antibodies across the placenta and in breast milk from mothers on intravenous immunoglobulin (p )
Patricia Palmeira, Beatriz T. Costa-Carvalho, Christina Arslanian, Gerlândia N. Pontes, Aparecida T. Nagao, Magda M. S. Carneiro-Sampaio
Published Online: Feb 10 2009 7:54PM
DOI: 10.1111/j.1399-3038.2008.00828.x
 

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PTGDR is not a major candidate gene for asthma and atopy in Chinese children (p )
Ting Fan Leung, Chung Yi Li, Alice P. S. Kong, Iris H. S. Chan, Maggie C. Y. Ng, Michael H. M. Chan, Wing Yee So, Gary W. K. Wong, Christopher W. K. Lam, Juliana C. N. Chan
Published Online: Feb 10 2009 7:53PM
DOI: 10.1111/j.1399-3038.2008.00835.x
 

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The outcome of patients with unclassified hypogammaglobulinemia in early childhood (p )
Necil Kutukculer, Nesrin Gulez
Published Online: Jan 31 2009 12:26PM
DOI: 10.1111/j.1399-3038.2008.00845.x
 

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A unique plasma proteomic profiling with imbalanced fibrinogen cascade in patients with Kawasaki disease (p )
Hong-Ren Yu, Ho-Chang Kuo, Jiunn-Ming Sheen, Lin Wang, I-Chun Lin, Chih-Lu Wang, Kuender D. Yang
Published Online: Jan 18 2009 11:20PM
DOI: 10.1111/j.1399-3038.2008.00844.x
 

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No association between tuberculin skin test and atopy in a bacillus Calmette-Guérin vaccinated birth cohort (p )
Aarif O. Eifan, Tunc Akkoc, Cevdet Ozdemir, Nerin N. Bahceciler, Isil B. Barlan
Published Online: Dec 22 2008 12:26PM
DOI: 10.1111/j.1399-3038.2008.00846.x
 

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Allergic rhinitis in children: Incidence and treatment in Dutch general practice in 1987 and 2001 (p )
Cindy M. A. de Bot, Heleen Moed, François G. Schellevis, Hans de Groot, Roy Gerth van Wijk, Johannes C. van der Wouden
Published Online: Dec 5 2008 12:20PM
DOI: 10.1111/j.1399-3038.2008.00829.x
 

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Cord blood cytokines and chemokines and development of allergic disease (p )
Martina Sandberg, Anne Frykman, Jan Ernerudh, Göran Berg, Leif Matthiesen, Christina Ekerfelt, Lennart J. Nilsson, Maria C. Jenmalm
Published Online: Oct 16 2008 12:26PM
DOI: 10.1111/j.1399-3038.2008.00794.x
 

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The interaction between early life upper respiratory tract infection and birth during the pollen season on rye-sensitized hay fever and ryegrass sensitization – a birth cohort study (p )
Andrew Kemp, Anne-Louise Ponsonby, Terry Dwyer, Jennifer Cochrane, Angela Pezic, Alan Carmichael, John Carlin, Graeme Jones
Published Online: Oct 13 2008 6:05AM
DOI: 10.1111/j.1399-3038.2008.00817.x
 

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Anti-asthmatic drug prescriptions to an Italian paedriatic population (p )
Marina Bianchi, Antonio Clavenna, Lorena Labate, Angela Bortolotti, Ida Fortino, Luca Merlino, G. Walter Locatelli, Gianemilio Giuliani, Maurizio Bonati
Published Online: Sep 3 2008 5:38AM
DOI: 10.1111/j.1399-3038.2008.00797.x
 

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Prevalence of self-perceived allergic diseases and risk factors in Italian adolescents (p )
Sonia Brescianini, Barbara Brunetto, Patrizia Iacovacci, Cristina D’Ippolito, Giuseppina Alberti, Maria Antonietta Schirru, Maria Antonietta Stazi, Carlo Pini, Gabriella Di Felice, Bianca Barletta
Published Online: Aug 15 2008 5:47AM
DOI: 10.1111/j.1399-3038.2008.00793.x
 

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Copyright © 2009, Clinical Pediatric Food Allergy Information Education Network. All rights reserved.

Clinical Anatomy_ Applied Anatomy for Students and Junior Doct.pdf

Grant’s Dissector.pdf

ANESTHESIOLOGY
Barash Clinical Anesthesia 5th ed.pdf
Miller’s Anesthesia.pdf

BIOCHEMISTRY
Harper’s illustrated biochemistry 26ed.pdf
Harper’s illustrated biochemistry 27th edition.chm
Color Atlas of Biochemistry 2nd Ed J.Koolman K-H. Roehm Thieme 2005.pdf

CARDIOLOGY
ABC of Interventional Cardiology.pdf
Advanced Interventional Cardiology.pdf
Gulizia – Emerging Pathologies in Cardiology.pdf
Cannon – Critical Pathways in Cardiology 2001.pdb
Cardiology cd.exe
Wagner – Marriott’s Practical Electrocardiography 10th ed.pdb

CLINICAL EPIDEMIOLOGY
Basic Epidemiology – Beaglehole , Bonita.pdf
Clinical_Epidemiology__Robert_Fletcher.pdf
Pinciples of Epidemiology, An Introduction to Applied

evidence_base_of_clinical_diagnosis.pdf

Evidence-Based Imaging – Optimizing Imaging in Patient Care.pdf

Evidence-based Medicine Workbook.pdf

Evidence Based Practice in Primary Care [ILLUSTRATED].pdf

DERMATOLOGY
Atlas of Dermatology Schering Co USAss.pdf
Fitzpatrick – Dermatology 5th ed 2005.CHM
Fitzpatrick’s Dermatology In General Medicine 6th ed.pdb
Hall – Sauer’s Manual of Skin Diseases 8th ed.pdb

Handbook of Skin Diseases.pdf

EMERGENCY MEDICINE & ICU
Wolfson – The Clinical Practice of Emergency Medicine 3rd ed.pdb
Pediatric Emergency Medicine. (a comperhensive study guide). 2nd eition,2007.CHM
An Introduction to Clinical Emergency Medicine.pdf
Cline – Emergency Medicine – A Comprehensive Study
Intensive and Critical Care Medicine.pdf
Irwin and Rippe’s Intensive Care Medicine 5th ed.pdb
Noble – Textbook of Primary Care Medicine 3rd ed
Field Guide to Bedside Diagnosis, 2e 2006.CHM.part
Rosen’s Emergency Medicine.chm

ENDOCRINOLOGY
Williams Textbook of Endocrinology 10ed.pdf
Handbook of Diagnostic Endocrinology.pdf

FAMILY MEDICINE & GERIATRICS
CURRENT Diagnosis & Treatment in Family Medicine.chm
Evans – Oxford Textbook of Geriatric Medicine.pdb
Geriatric Medicine An Evidence-based Approach.pdf

HEMATOLOGY & IMMUNOLOGY
Modern Hematology Biology and Clinical Management 2nd ed.pdf
Oxford Handbook of Hematology.pdf
Color Atlas of Hematology.pdf
Wintrobe’s Clinical Hematology 11th.pdb
Adelman – Manual of Allergy and Immunology Diagnosis.pdb
World of Microbiology and Immunology.pdf
HISTOLOGY
Histology Image Review.CHM
Junqueira Carneiro – Basic Histology Text and Atlas 11ed.chm
Kuehnel – color atlas of cytology, histology and microscopic anatomy.pdf

INTERNAL MEDICINE

Harrison’s principles of internal medicine 17ed.chm
Harrison’s principles of internal medicine 16ed.pdf
Harrison_s_Manual_of_Medicine_16th_Edition.pdf
Cecil – Textbook of Medicine.pdf
Kelly’s Textbook of Medicine.pdb
Mayo Clinic Internal Medicine Concise Textbook.pdf
Lippincott.Wilkins.&.Williams.Yamada’s.Textbook.of.Gastroenterology.pdf
Schrier – Manual of Nephrology Diagnosis and Therapy 5th ed.pdb
Bates guide to physical examination+MCQs.pdf

Clinical Interviewing.pdf

Clinical Medicine – 6th edition.pdf

LR – Pocket Medicine 3rd Edition.pdf

Problem Solving in Clinical Medicine.pdf

MICROBIOLOGY
Jawetz, Melnick, & Adelberg’s Medical Microbiology, 24th Ed 2007 McGraw Hill.chm
Laboratory Exercises In Microbiology.pdf
Clinical Microbiology made simple.pdf
The Desk Encyclopedia Microbiology.pdf
Lippincott Illustrated Reviews_Microbiology
Essential Microbiology.pdf
Glazer Microbial Biotechnology – Fundamentals of Applied Microbiology 2nd ed.pdf

World of Microbiology and Immunology.pdf

NEUROANATOMY & NEUROLOGY
Snell’s clinical neuroanatomy
Neuroanatomy An Atlas of Structures, Sections, and Systems – Duane E. Haines.pdf
Adams and Victor’s Principles of Neurology 8th.pdf
Atlas of functional neuroanatomy 2nd ed.pdf

Cranial Nerves Functional Anatomy (2005).pdf

Differential Diagnosis in Neurology and Neurosurgery.pdf

Goetz textbook of neurology.pdb
The Clinical Science of Neurologic Rehabilitation (Contemporary Neurology Series, 66) (2003).pdf
Neuroanatomy – Atlas of Structures Sections Systems 6ed.pdf
Neuroscience – D.Purves, et al.pdf
Merritt – Merritt’s Neurology 10th Ed.pdb
Handbook of Neurology.CHM

Nervous System and Sensory Organs – Color Atlas and Textbook of Human Anatomy – Volume 3.pdf

OBSTETRICS-GYNECOLOGY
Benson Pernolls Handbook of Obstetrics-Gynecology.pdf
Williams Obstetrics 22nd Edition.pdf
Berek & Novak’s Gynecology 14th ed.pdf
Novak’s Gynecology 13ed.pdb
Obstetrics And Gynecology At A Glance.pdf
Stenchever – Comprehensive Gynecology 4th ed – Big Images.pdb
Havens – Manual of Outpatient Gynecology 4ed.pdb
The Johns Hopkins Manual of Gynecology and Obstetrics 2nd ed.pdb

Obstetrics and Gynecology An Illustrated Colour Text.pdf

ONCOLOGY

Weinstein Pediatric Oncology – Pediatric_Lymphomas.pdf

Manual of Pediatric Hematology and Oncology.pdf

Berek Practical Gynecologic Oncology 3ed.pdb

Rosenberg – Cancer – Principles and Practice of Oncology 6th.pdb

Pizzo – Principles and Practice of Pediatric Oncology 4th Ed.pdb

ORTHOPEDICS & RHEUMATOLOGY
MILLER’S_REVIEW_OF_ORTHOPEDICS.pdf
Manual of Rheumatology and Outpatient Orthopedic Disorders Diagnosis and Therapy 4th ed.pdb
Kelley’s Textbook of Rheumatology 6th Edition, 2-Volume Set – ISBN.pdb
DeLee and Drez’s – Orthopaedic Sports Medicine. Editor DeLee (2nd Ed. 2003).pdb
Current Diagnosis & Treatment in Orthopedics 3rd ed.pdb

Pediatric Orthopedics for Primary Care Physicians.pdf

Pediatric Orthopedics in Practice.pdf

PARASITOLOGY
Gillespie & Pearson – Principles and Practice of Clinical Parasitology 2001
Clinical Parasitology.pdf
Dictionary of Parasitology.pdf

PATHOLOGY
Robbins Pathologic Basis of Disease 7th ed 2005.pdf
stedmans Pathology&Lab medicine
Scott_Tietz’s Applied Laboratory Medicine 2nd ed.pdf
Ravel – Clinical Laboratory Medicine – Clinical Applications.pdb

PATHOPHYSIOLOGY OF DISEASE.pdf

PEDIATRICS
Nelson Textbook of Pediatrics 17th ed.pdf
Nelson Essentials of PEDIATRICS.CHM
Current Strategies in Pediatrics 2004.pdf

Pediatric.Musculoskeletal.Disease.pdf

Pediatric.Radiography.3HAXAP.pdf

Treatment.of.Pediatric.Neurologic.Disorders.3HAXAP.pdf

PHARMACOLOGY
Katzung basic clinical pharmacology 10ed.pdf
Katzung basic clinical pharmacology 9ed.pdf
Basic Clinical Pharmacology – 10th Ed.chm
Color Atlas of Pharmacology 3rdEd.pdf

Color Atlas of Pharmacology.pdf
Color Atlas Of Pharmacology,2Nd Ed (By H Lullmann Et Al ,Thieme 2000,Isbn 0865778434).pdf
Lippincott Illustrated Reviews_Pharmacology 2nd ed 2000
Edwards – Principles and Practice of Pharmaceutical Medicine 2nd ed.pdf
Goodman Gilman’s – The Pharmacological Basis of Therapeutics 11th Edition

PHYSIOLOGY
Review of Medical Physiology 21 Edition -William F. Ganong.chm
Physiology – Berne and Levy – 5th Edition.chm
physiology – Guyton.pdf

PSYCHIATRY
Kaplan & Sadock’s Comprehensive Textbook of Psychiatry (2 Volume Set) 7th Ed (Lippincott Williams & Wilkins).pdf
Lewis – Child and Adolescent Psychiatry A Comprehensive Textbook 4th Edition

RADIOLOGY
Dahnert – radiology review manual 4th ed.pdf
Getting Started in Clinical Radiology – from Image to Diagnosis.pdf
Emergency Radiology.pdf
WHO manuals of diagnostic imaging – Radiographic Anatomy and Interpretation of the Musculoskeletal System.pdf
Churchill Livingstone – 2001 – Grainger & Allison’s Diagnostic Radiology. A Textbook of Medical I.pdb

SURGERY
Schwartz Manual of Surgery 8ed.pdf
Oxford Textbook of Surgery (2ed).pdf
Clinical Surgery in General R.M.Kirk 4th Ed 2004.pdf
Wilmore – ACS Surgery – Principles and Practice 2nd ed.zip
Morris – Oxford Textbook of Surgery 2nd ed.pdb
Sabiston Textbook of Surgery, 16th Edition.pdf

Current Surgical Diagnosis and Treatment 11ed With images.pdb
MANUALS, DICTIONARIES, ATLAS
Current Clinical Strategies. Physicians’ Drug Manual. Side Effects, Drug Interactions, and Newly Approved Drugs. 2003 Ed.pdf
Dale – Infectious Diseases The Clinician’s Guide to Diagnosis, Treatment, and Prevention – Big Images.pdb
Bennett and Brachman’s Hospital Infections (Lippincott, 2007).chm
LR – Pocket Medicine 3rd Edition.pdf
Lippincott Williams Wilkins 2003 Medical Terminology An Illustrated Guide 4th Ed.pdf
Merck Manual 17th.Ed.pdb
Pocket Atlas of Radiographic Anatomy 2nd ed, 2000.pdf
Pocket Guide to Diagnostic Tests-0838581358.pdf
Pocket.Guide.to.Musculoskeletal.Diagnosis.3HAXAP.pdf
Oxford Textbook Of Rheumatology, 2nd ed (1998).pdb
Oxford_textbook_of_public_health_4th_ed.pdb
Manual of Clinical Problems In Pediatrics 5th Edition (2000).pdb
Manual of Family Practice 2nd ed.pdb
Ferri’s Clinical Advisor 2004 – Instant Diagnosis and Treatment. 6th edition.pdb
Pocket Atlas of Echocardiography.pdf
Pocket Atlas Of Radiographic Anatomy 2d ed – Torsten B. Moller, Emil Reif.pdf
Pocket_Atlas_of_Human_Anatomy__H._Feneis__W._Dauber._4th_Ed._2000_.pdf
Pocket guide to diagnostic tests.chm
Stedman’s Electronic Medical Dictionary 6th Edition.pdf
Colour Atlas of Anatomical Pathology.pdf
Glossary of Biotechnology Terms, Third Edition.pdf
Clinical Neuropathology Text and Color Atlas.pdf
An Atlas Of Back Pain.pdf
An Atlas of Headache.maxiwarez.pdf
Atlas of Clinical Diagnosis 2nd Ed (2003).pdf
Henry Clinical Diagnosis and Management by Laboratory Methods 21st ed.chm

FLASH CARDS
- ANATOMY (NETTER)
- ANATOMY (ROHEN’S)
- PATHOLOGY
- PHARMACOLOGY

ABC SERIES

ABC of AIDS.pdf
ABC of Antenatal Care.pdf
ABC of Antithrombotic Therapy.pdf
ABC of Arterial and Venous Disease.pdf
ABC of Burns.pdf
ABC of Clinical Electrocardiography.pdf
ABC of Clinical Genetics.pdf
ABC of Clinical Haematology.pdf
ABC of Colorectal Cancer.pdf
ABC of Conflict and Disaster.pdf
ABC of Dermatology.pdf
ABC of Diabetes.pdf
ABC of Eyes.pdf
ABC of First Year.pdf
ABC of Heart failure.pdf
ABC of Intensive Care.pdf
ABC of Interventiona Cardiology 2004.pdf
ABC of Learning Teaching Medicine.pdf
ABC of Nutrition, 4th Edition.pdf
ABC of Occupational and Environmental Medicine.pdf
ABC of Preterm Birth.pdf
ABC of Psychological Medicine.pdf
ABC of Resuscitation.pdf
ABC of Sexually Transmitted Infections.pdf
ABC of Spinal Cord Injury 4th Ed.pdf
ABC of Subfertility.pdf
ABC of the Liver Pancreas and Gall Bladder.pdf
ABC of the Upper Gastrointestinal.pdf

—————————————————————
US MLE REVIEW SERIES

anatomy.pdf
basic epidemiology -beaglehole,bonita.pdf
behavioral sciences.pdf
beyond basic resp.pdf
biochemistry.pdf
clinical anatomy 11ed.pdf
clinical epidimiology -robert fletcher.pdf
kaplan lecture notes.pdf
lecture on visuals.pdf
microbiology,immunology.pdf
pathology.pdf
pharmacology.pdf
physiology.pdf
principles of epidemiology.pdf
Qbook.pdf
upper extremities cadaver pics.pdf
kaplan medical timeline.pdf

OTHERS:

1. Journal Medical Passwords 2003.pdf
——————————————————
1. Anatomy.tv – Anatomy Study Guides.chm
2. Cranial_Nerves_Functional_Anatomy.pdf
3. Outline of Biology – Fried, George H..pdf
——————————————————
1. Gray’s Anatomy for Students.chm
2. Chest Radiology The Essentials, 2nd Edition.CHM
3. Clinical Anatomy by Regions – 8th Ed.CHM
4. Grant’s Dissector.pdf
5. Clinical Radiology Made Ridiculously Simple (MedMaster Series 2003 Ed
6. Clinical Anatomy_ Applied Anatomy for Students and Junior Doct.pdf
7. The Medical Student’s Guide to the Plain Chest Film.pdf
——————————————————
1. Clinical Interviewing 3rd edition.pdf
2. What They Didnt Teach You at Medical School.pdf
3. Medical English.pdf
4. Medical Law and Moral Rights (Springer, 2005).pdf
5. Neuroethics.pdf
——————————————————
1. Ferri’s Clinical Advisor 2008_ Instant Diagnosis and Treatment.CHM
2. Current Medical Diagnosis & Treatment 2007, 46th Ed.chm
3. Handbook of Neurology.CHM
4. Professional Guide to Signs and Symptoms – 5th Ed.chm
5. Colour Atlas of Anatomical Pathology.pdf
6. Glossary of Biotechnology Terms, Third Edition.pdf
7. Clinical Neuropathology Text and Color Atlas.pdf
8. An Atlas Of Back Pain.pdf
9. An Atlas of Headache.maxiwarez.pdf
10. Atlas of Clinical Diagnosis 2nd Ed (2003).pdf
11. Atlas of functional neuroanatomy 2nd ed.pdf
12. Kahle, Color Atlas of Human Anatomy, vol 3 (2003).pdf
13. Neuroanatomy An Atlas of Structures, Sections, and Systems – Duane E. Haines.pdf
14. Pocket Atlas of Echocardiography.pdf
15. Pocket Atlas Of Radiographic Anatomy 2d ed – Torsten B. Moller, Emil Reif.pdf
16. Pocket_Atlas_of_Human_Anatomy__H._Feneis__W._Dauber._4th_Ed._2000_.pdf
17. Stedman’s Electronic Medical Dictionary 6th Edition.pdf
——————————————————
1. Skill 01[1].Temperature..pdf
2. Skill 02[1]..Pulse.pdf
3. Skill 03[1]..Respiration.pdf
4. Skill 04[1]..Blood Pressure.pdf
5. Skill 05[1]..Pulse Oximetry.pdf
6. Skill 06[1]..Capillary Blood Draw.pdf
7. Skill 07[1]..Venipuncture.pdf
8. Skill 08[1]..Blood Draw from a Central Venous Catheter.pdf
9. Skill 09[1]..Nasopharyngeal Swab.pdf
10. Skill 10[1]..Throat Culture.pdf
11. Skill 11[1]..Collection of Stool Specimen.pdf
12. Skill 12[1]..Collection of Urine Specimen.pdf
13. Skill 13[1]..Collection of a Midstream.pdf
14. Skill 14[1]..Assisting with Child during Bone Marrow.pdf
15. Skill 15[1]..Assisting with Child during Lumbar Puncture.pdf
16. Skill 16[1]..Assisting with Collection of Cerebrospinal.pdf
17. Skill 17[1]..Sponge Bath.pdf
18. Skill 18[1]..Insertion of a Peripheral IV Line.pdf
19. Skill 19[1]..Dressing Change Central Venous Line.pdf
20. Skill 20[1]..Insertion of a Nasogastric Tube.pdf
21. Skill 21[1]..Management of Gastrointestinal Suction.pdf
22. Skill 22[1]..Nasogastric Tube Irrigation.pdf
23. Skill 23[1]..Nasogastric Tube Lavage.pdf
24. Skill 24[1]..Administration of a Bolus Feeding.pdf
25. Skill 25[1]..Administration of NG, NJ, Gastrostomy and.pdf
26. Skill 26[1]..Changing a Fecal Ostomy Appliance.pdf
27. Skill 27[1]..Emptying an Ostomy Pouch.pdf
28. Skill 28[1]..Administration of Enemas.pdf
29. Skill 29[1]..Urinary Catheterization.pdf
30. Skill 30[1]..Petaling a Cast.pdf
31. Skill 31[1]..Pin Site Care.pdf
32. Skill 32[1]..Care of the Child in an External Fixation.pdf
33. Skill 33[1]..Pin Care, External Fixation Device.pdf
34. Skill 34[1]..EVD Maintaining System at Correct Level and Functioning.pdf
35. Skill 35[1]..EVD Client Assessment.pdf
36. Skill 36[1]..EVD Monitoring Cerebrospinal Fluid (CSF).pdf
37. Skill 37[1]..EVD Changing the Drainage Bag.pdf
38. Skill 38[1]..EVD General Nursing Care and Safety.pdf
39. Skill 39[1]..Assisting with Chest Tube Insertion.pdf
40. Skill 40[1]..Preparing the Chest Tube Drainage System.pdf
41. Skill 41[1]..Care of the Child with a Chest Tube.pdf
42. Skill 42[1]..Assisting with Removal of Chest Tube.pdf
43. Skill 43[1]..Oxygen Administration.pdf
44. Skill 44[1]..Bulb Suctioning.pdf
45. Skill 45[1]..Nasotracheal Suctioning.pdf
46. Skill 46[1]..Tracheostomy Monitoring.pdf
47. Skill 47[1]..Tracheostomy Tube Change.pdf
48. Skill 48[1]..Tracheostomy Tube.pdf
49. Skill 49[1]..Tracheostomy Suctioning.pdf
50. Skill 50[1]..Endotracheal Tube Monitoring (ETT).pdf
——————————————————

Churchill Livingstone – 2001 – Grainger & Allison’s Diagnostic Radiology. A Textbook of Medical I.pdb
Classifications and Scores of the Shoulder – Habermeyer.pdf
Clinical Examination of Musculoskeletal System – Assessing Rheumatic Conditions.pdf
Clinical Interviewing.pdf
Clinical Orthopaedic Examination, Fifth Edition (2004).pdf
Clinical Tests for the Musculoskeletal System.pdf
Clinical.Anatomy.11ed.1405138041.Oct.2006.pdf
Clinical.Knowledge.Management.Opportunities.and.Challenges.pdf
clinical_evidence_vol_10.pdb
clinical_evidence_vol_9.pdb
clinical_laboratory_medicine_-_clinical_applications.pdb
Clinician’s Pocket Reference_0838515525.pdf
Color Atlas of Pharmacology.pdf
Color Atlas of Physiology.pdf
Common Symptom Answer Guide.pdf
Complementary Therapies in Neurology.pdf
Comprehensive Management of Chronic Obstructive Pulmonary Disease (2002) – COPD.iso
Core Topics in Pain.pdf
Cranial Nerves Functional Anatomy (2005).pdf
Current Diagnosis & Treatment in Orthopedics 3rd ed.pdb
Current Medical Diagnosis & Treatment, 2005 full pic.pdb
DeLee and Drez’s – Orthopaedic Sports Medicine. Editor DeLee (2nd Ed. 2003).pdb
Differential Diagnosis in Neurology and Neurosurgery.pdf
Drawing the Line. Art Therapy with the Difficult Client.pdf
Dynamics_of_Human_Gait.pdf
Electrodiagnosis in Diseases of Nerve and Muscle – Principles and Practice.chm
Elsevier’s Medical Terminology for the Practicing Nurse (1998).pdf
Encyclopedia of Infectious Diseases.pdf
Essentials of Complementary and Alternative Medicine.pdf
Essentials_of_Physical_Medicine_and_Rehabilitation.pdb
Evaluation of the Low Back Pain Practice Guideline Implementation in the Army.pdf
Evidence Based Practice in Primary Care [ILLUSTRATED].pdf
Evidence-Based Imaging – Optimizing Imaging in Patient Care.pdf
Evidence-based Medicine Workbook.pdf
evidence_base_of_clinical_diagnosis.pdf
Exercise Leadership in Cardiac Rehabilitation – An Evidence-based Approach – 0470019719.pdf
Ferri’s Clinical Advisor 2004 – Instant Diagnosis and Treatment. 6th edition.pdb
Foundations of Sport-Related Brain Injuries.pdf
Fractures_Classification_in_Clinical_Practice__2006_.pdf
Fractures_in_children_5ed.pdb
Functional Neuroanatomy of Pain.pdf
General Practice, 3rd Edition (J. Murtagh).pdb
Geriatric Medicine An Evidence-based Approach.pdf
Hand Bone Age.pdf
Handbook of couples therapy.pdf
Healing or Stealing. Medical Charlatans in the New Age.pdf
Healing_Back_Pain_The_Mind.pdf
How to Present at Meetings 2001.pdf
How to Read a Paper.pdf
Human Biology_0071218068.pdf
Human Body Dynamics – classical mechanics and human movement – A.Tozeren.pdf
Image-guided spine interventions.pdf
Information Technologies in Medicine – Volume I.pdf
Instant Pain Control – Using the Body’s Trigger Points.djvu
Interpretation of Diagnostic Tests 7th ed.pdb
Interviewing And Diagnostic Exercises For Clinical And Counseling Skills Building – ISBN 08058464.pdf
Kelley’s Textbook of Rheumatology 6th Edition, 2-Volume Set – ISBN.pdb
Lab Notes Guide to Lab and Diagnostic Tests (2005).pdf
Learning_Medicine_An_Informal_Guide_to_a_Career_in_Medicine.pdf
Living well with Parkinson’s.pdf
Lovell_and_winter_s_pediatric_orthopaedics_3rd_ed.pdb
Managing the symptoms of multiple sclerosis.pdf
Managing Your Multiple Sclerosis.pdf
Manual of Clinical Problems In Pediatrics 5th Edition (2000).pdb
Manual of Family Practice 2nd ed.pdb
Manual of Rheumatology and Outpatient Orthopedic Disorders Diagnosis and Therapy 4th ed.pdb
Marketing health services.pdf
Massage For Dummies.pdf
MCQ.Companion.to.Applied.Radiological.Anatomy.3HAXAP.pdf
Means Ends and Medical Care.pdf
Medical and Psychosocial Aspects of Chronic Illness and Disability, Third Edition (2005).pdf
Medical Malpractice – A Physician’s Sourcebook.pdf
Medical_Physiol_2nd_Ed.pdf
Merritt – Merritt’s Neurology 10th Ed.pdb
MILLER’S_REVIEW_OF_ORTHOPEDICS.pdf
Modern Neuromuscular Techniques (Modern Neuromuscular Techniques (WCD)) (2003).ISO
MP Van De Graaff Human Anatomy.pdf
Musculoskeletal.Diseases.DIAGNOSTIC IMAGING AND INTERVENTIONAL TECHNIQUES.pdf
Nelson.Textbook.of.Pediatrics.17th.ed – Behrman.pdb
Nervous System and Sensory Organs – Color Atlas and Textbook of Human Anatomy – Volume 3.pdf
Neuroanatomy – Atlas of Structures Sections Systems 6ed.pdf
Neuroscience – D.Purves, et al.pdf
Neurotransmitters, Drugs and Brain Function Wiley (2001).pdf
Nurses manual of laboratory and diagnostic tests 4th Ed 2003.pdf
Nursing practice in multiple sclerosis – a core curriculum.pdf
Occupational Health Practice – Arnold.Publishers.Fourth.EditionISBN0750627204.pdf
Opportunities in Physician Careers_0071438483.pdf
Outpatient and Primary Care Medicine, 2005 Edition (2004).pdf
Oxford Textbook Of Rheumatology, 2nd ed (1998).pdb
Oxford_Dictionary_of_Medical_Quotations.pdf
Oxford_textbook_of_public_health_4th_ed.pdb
Pediatric Musculoskeletal Diseases.pdf
Pediatric Radiography.pdf
Pain and Depression – An Interdisciplinary Patient-centered Approach.pdf
Pain.Medicine.and.Management.Just.the.Facts.pdf
Pain.Psychological.Perspectives.eBook-DDU.pdf
PATHOPHYSIOLOGY OF DISEASE.pdf
Pediatric Orthopedics for Primary Care Physicians.pdf
Pediatric Orthopedics in Practice.pdf
Physical Medicine and Rehabilitation Board Review.pdf
Pocket Atlas of Radiographic Anatomy 2nd ed, 2000.pdf
Pocket Guide to Diagnostic Tests-0838581358.pdf
Pocket.Guide.to.Musculoskeletal.Diagnosis.3HAXAP.pdf
Primary_care_medicine_office_evaluation_and_managem.pdb
Principles.and.Practice.of.Burn.Surgery.3HAXAP.pdf
Quick reference dictionary for massage therapy and bodywork.pdf
Robbins Pathologic Basis of Disease (with pictures).pdb
Rosen’s Emergency Medicine.chm
Scientific Writing Easy When You Know How (2002).pdf
Screening Notes Rehabilitation Specialists Pocket Guide (Davis Notes S) ISBN0803615736.pdf
Soft Tissue Rheumatology.CHM
Sports Injuries – Mechanisms, Prevention, Treatment. 2nd edition.pdb
SPORTS MEDICINE Just the Facts.pdf
strength training anatomy.pdf
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Textbook of Clinical Trials Wiley (2004).pdf
Textbook of Medical Physiology.pdf
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The Clinical Drug Therapy Rationales for Nursing Practice (Field Guide Series) (2006).pdf
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The Trigger Point Therapy Workbook – Your Self-Treatment Guide for Pain Relief – Clair Davies.pdf
The.Ultimate.New.York.Body.Plan.eBook-TLFeBOOK.pdf
TMJ Disorders and Orofacial.doc
Toward.Replacement.Parts.for.the.Brain.Implantable.Biomimetic.Electronics.PDF.eBook-YYePG.pdf
Trauma.E.Moore, et al – 5th edition.pdb
Treating Pediatric Bed-wetting With Acupuncture & Chinese Medicine.pdf
Treatment of Osteoarthritic Change in the Hip – Joint Preservation or Joint Replacement.pdf
Treatment.of.Pediatric.Neurologic.Disorders.3HAXAP.pdf
Tyranny of Health Doctors and the Regulation of Lifestyle.pdf
Understanding Human Anatomy and Physiology 5th edition.pdf
Using Alternative Therapies – A Qualitative Analysis.pdf
Visions of the Future. Chemistry and Life Science.pdf
Weight Training Basics.pdf
What They Didn’t Teach You at Medical School.pdf
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WHO manuals of diagnostic imaging – Radiographic Anatomy and Interpretation of the Musculoskeletal System.pdf
Who s who in orthopedics.pdf
World of Microbiology and Immunology.pdf
Writing Skills in Practice (Health Professionals).pdf

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Yudhasmara Foundation 

email : judarwanto@gmail.com, 

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Supported  by
CLINICAL PEDIATRIC ONLINE

Yudhasmara Foundation

JL Taman Bendungan Asahan 5 Jakarta Indonesia 102010

phone : 62(021) 70081995 – 5703646

email : judarwanto@gmail.com,

http://clinicalpediatric.wordpress.com/

Clinical and Editor in Chief :

DR WIDODO JUDARWANTO

Copyright © 2009, Clinical Pediatric Online Information Education Network. All rights reserved.

Supported  by
CLINICAL PEDIATRIC ONLINE

Yudhasmara Foundation

JL Taman Bendungan Asahan 5 Jakarta Indonesia 102010

phone : 62(021) 70081995 – 5703646

email : judarwanto@gmail.com,

http://clinicalpediatric.wordpress.com/

Clinical and Editor in Chief :

DR WIDODO JUDARWANTO

Copyright © 2009, Clinical Pediatric Online Information Education Network. All rights reserved.

Supported  by
CLINICAL PEDIATRIC ONLINE

Yudhasmara Foundation

JL Taman Bendungan Asahan 5 Jakarta Indonesia 102010

phone : 62(021) 70081995 – 5703646

email : judarwanto@gmail.com,

http://clinicalpediatric.wordpress.com/

Clinical and Editor in Chief :

DR WIDODO JUDARWANTO

Copyright © 2009, Clinical Pediatric Online Information Education Network. All rights reserved.

Supported  by
CLINICAL PEDIATRIC ONLINE

Yudhasmara Foundation

JL Taman Bendungan Asahan 5 Jakarta Indonesia 102010

phone : 62(021) 70081995 – 5703646

email : judarwanto@gmail.com,

http://clinicalpediatric.wordpress.com/

Clinical and Editor in Chief :

DR WIDODO JUDARWANTO

Copyright © 2009, Clinical Pediatric Online Information Education Network. All rights reserved.

Supported  by
CLINICAL PEDIATRIC ONLINE 

Yudhasmara Foundation 

JL Taman Bendungan Asahan 5 Jakarta Indonesia 102010

phone : 62(021) 70081995 – 5703646 

email : judarwanto@gmail.com,

http://clinicalpediatric.wordpress.com/

Clinical and Editor in Chief :

DR WIDODO JUDARWANTO 

Copyright © 2009, Clinical Pediatric Online Information Education Network. All rights reserved